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Table 4 Sensitivity, specificity, and positive/negative predictive values of CDX2 expression and CK7-/CK20+ immunophenotype in differentiating colorectal adenocarcinomas from pancreatic and gastric adenocarcinomas.

From: The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody

 

Sensitivity

Specificity

PPV

NPV

CK7-/CK20+

63.6%

96.7%

96.2%

67.2%

CDX2 > 5%

96.6%

54.9%

73.5%

92.6%

CDX2 > 50%

78.0%

84.6%

86.8%

74.8%

  1. PPV: Positive Predictive Value NPV: Negative Predictive Value