Table 1 Correlation between level of MAEL mRNA expression and clinicopathological features of ESCC patients.
From: MAEL as a diagnostic marker for the early detection of esophageal squamous cell carcinoma
| Â | Total | MAEL over expression | MAEL under expression | MAEL normal expression | P- Value |
|---|---|---|---|---|---|
Patients | 45 | 9(20 %) | 12(26.7 %) | 24(53.3 %) |  |
Mean age (Years, mean ± SD) | 61.56 ± 11.38 | 65.89 ± 1.92 | 59.25 ± 3.18 | 61.08 ± 2.64 | 0.232 |
Size (cm, mean ± SD) | 4.25 ± 1.91 | 3.48 ± 0.55 | 4.94 ± 0.72 | 4.19 ± 0.33 | 0.193 |
Sex | Â | Â | Â | Â | 0.252 |
Male | 25(55.6 %) | 7(77.8 %) | 5(41.7 %) | 13(54.2 %) |  |
Female | 20(44.4 %) | 2(22.2 %) | 7(58.3 %) | 11(45.8 %) |  |
Location | Â | Â | Â | Â | 0.245 |
Lower | 21(46.7 %) | 3(33.3 %) | 4(33.3 %) | 14(58.3 %) |  |
Middle | 24(53.3 %) | 6(66.7 %) | 8(66.7 %) | 10(41.7 %) |  |
Grade | Â | Â | Â | Â | 0.749 |
Well Differentiated | 9(20 %) | 2(22.2 %) | 3(25 %) | 4(16.7 %) |  |
Moderately Differentiated | 31(68.9 %) | 5(55.6 %) | 8(66.7 %) | 18(75 %) |  |
Poorly Differentiated | 5(11.1 %) | 2(22.2 %) | 1(8.3 %) | 2(8.3 %) |  |
Lymph node metastasis | Â | Â | Â | Â | 0.564 |
Yes | 22(48.9 %) | 3(33.3 %) | 6(50 %) | 13(54.2 %) |  |
No | 23(51.1 %) | 6(66.7 %) | 6(50 %) | 11(45.8 %) |  |
Stage |  |  |  |  | < 0.001 |
I/II | 26(57.8 %) | 8(88.9 %) | 5(41.7 %) | 13(54.2 %) |  |
III/IV | 19(42.2 %) | 1(11.1 %) | 7(58.3 %) | 11(45.8 %) |  |
Depth of tumor invasion (T) | Â | Â | Â | Â | 0.017 |
T1,2 | 7(15.6 %) | 4(44.4 %) | - | 3(12.5 %) |  |
T3,4 | 38(84.4 %) | 5(55.6 %) | 12(100 %) | 21(87.5 %) |  |