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Table 1 Racial differences in the different exon mutations and the specific mutation sites for each exon mutation

From: Danon disease: a case report and literature review

 

Asian (n = 26)

 

Caucasian (n = 26)

 

P value

Exon 1

n = 2

29_35dupCGGGCTC

n = 1

52 T → C

1.00

  

64G → T

   

Exon 2

n = 0

 

n = 6

102_103delAG

0.023

    

121delT

 
    

135dupA

 
    

137G → A

 
    

138G → A

 
    

179delC

 

Exon 3

n = 6

189_190delTG

n = 2

294G → A

0.248

  

241delG

 

294G → A

 
  

257_258delCC

   
  

317_320dupCATA

   
  

320_321insCATC

   
  

369_370delTG

   

Exon 4

n = 1

467 T → G

n = 3

453delT

0.610

    

467 T → G

 
    

605C → G

 

Exon 5

n = 4

573delA

n = 2

680_701del

0.668

  

718C → T

 

716delT

 
  

718C → T

   
  

741 + 1G → T

   

Exon 6

n = 7

749C → G

n = 1

796_797insC

0.049

  

749C → A

   
  

808dupG

   
  

808dupG

   
  

808_809insG

   
  

821_822delTT

   
  

839delA

   

Exon 7

n = 1

877Cys → Thr

n = 5

928G → A

0.191

    

928G → A

 
    

928G → A

 
    

928G → A

 
    

928G → A

 

Exon 8

n = 2

973dupC

n = 6

940delG

0.248

  

1009_1010delGT

 

961 T → C

 
    

962G → A

 
    

973insC

 
    

1075C → T

 
    

Single nucleotide delete

 

Exon 9

n = 3

1204A → T

n = 0

 

0.235

  

1205delC

   
  

1205delC

   
  1. The chi-square test was used for statistical analysis
  2. Bold values indicate significance at p-value < 0.05