Table 2 Histopathological characteristics of different sebaceous lesions
Variables | Sebaceous hyperplasia (n = 52) | Sebaceoma (n = 15) | Sebaceous adenoma (n = 13) | Extraocular sebaceous carcinoma (n = 20) | Periocular sebaceous carcinoma (n = 23) |
|---|---|---|---|---|---|
Pagetoid appearance | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 3 (15.0%) | 10 (43.4%) |
Vascular invasion | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (5.0%) | 3 (13.0%) |
Neural invasion | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (5.0%) | 4 (17.3%) |
Atypical mitosis | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 7 (35.0%) | 17 (73.9%) |
Cystic appearance | 0 (0.0%) | 5 (33.3%) | 4 (30.8%) | 4 (20.0%) | 7 (30.4%) |
Ulceration and erosion | 0 (0.0%) | 5 (33.3%) | 7 (53.8%) | 15 (75.0%) | 18 (78.2%) |
Ductal differentiation | 0 (0.0%) | 12 (80.0%) | 2 (15.4%) | 16 (80.0%) | 5 (21.7%) |
Squamous differentiation | 0 (0.0%) | 7 (46.7%) | 1 (7.7%) | 11 (55.0%) | 10 (43.5%) |
Basaloid cell count | Â | Â | Â | Â | Â |
 < 50% | 52 (100.0%) | 0 (0.0%) | 13 (100.0%) | 1 (5.0%) | 0 (0.0%) |
 > 50% | 0 (0.0%) | 15 (100.0%) | 0 (0.0%) | 19 (95.0%) | 23 (100.0%) |
Tumor margin | Â | Â | Â | Â | Â |
 Circumscribed | 52 (100.0%) | 15 (100.0%) | 13 (100.0%) | 3 (15.0%) | 4 (17.4%) |
 Infiltrative | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 17 (85.0%) | 19 (82.6%) |
Necrotic area | Â | Â | Â | Â | Â |
 None | 52 (100.0%) | 14 (93.3%) | 13(100.0%) | 7 (35.0%) | 10 (43.5%) |
 Single cell | 0 (0.0%) | 1 (6.7%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
 Narrow | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 7 (35.0%) | 9 (39.1%) |
 Extensive | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 6 (30.0%) | 4 (17.4%) |
Cell differentiation | Â | Â | Â | Â | Â |
 Well | 52 (100.0%) | 6 (40.0%) | 12 (92.3%) | 0 (0.0%) | 4 (17.4%) |
 Moderate | 0 (0.0%) | 9 (60.0%) | 1 (7.7%) | 9 (45.0%) | 13 (56.5%) |
 Poor | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 11 (55.0%) | 6 (26.1%) |
Tumor growth pattern | Â | Â | Â | Â | Â |
 Lobular | 52 (100.0%) | 15 (100.0%) | 13 (100.0%) | 10 (50.0%) | 11 (47.8%) |
 Comedo | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 6 (30.0%) | 4 (17.4%) |
 Papillary | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
 Mixed | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 4 (20.0%) | 8 (34.8%) |
Peripheral basaloid layers | Â | Â | Â | Â | Â |
 ≤ 2 | 52 (100.0%) | 0 (0.0%) | 9 (69.2%) | 1 (5.0%) | 0 (0.0%) |
 > 2 | 0 (0.0%) | 15 (100.0%) | 4 (30.8%) | 19 (95.0%) | 23 (100.0%) |
Mitotic activity (per 10 HPF) | Â | Â | Â | Â | |
 0–1 | 52 (100.0%) | 6 (40.0%) | 10 (76.9%) | 1 (5.0%) | 1 (4.3%) |
 2–5 | 0 (0.0%) | 6 (40.0%) | 2 (15.4%) | 2 (10.0%) | 4 (17.4%) |
 > 5 | 0 (0.0%) | 3 (20.0%) | 1 (7.7%) | 17 (85.0%) | 18 (78.3%) |