Fig. 2

Co-expression analysis of BNST-related genes using WGCNA. A Cluster dendrogram of control and tumor samples of BNST patients. B Scale-free fit index (left) and average connectivity (right) correspond to different values of soft thresholding power β. The red line represents a correlation coefficient of 0.9. C Hierarchical clustering of feature gene modules summarizing the clustering analysis. D Dendrogram of co-expressed genes, with each leaf representing a different gene module. E Scatter plot showing the correlation between the brown module and tumor clinical features, with P-values shown in the Figure. F Heatmap of the correlations between different modules and BNST in the merged dataset. Each cell contains the corresponding correlation and P-value. G Venn diagram showing the intersection of differentially expressed genes and brown module genes