Fig. 4
Analysis of immune cell composition and correlation in BNST samples. A Bar chart showing the analysis of immune cell composition in normal tissue and tumor tissue of BNST patients. The x-axis represents the sample number, and the y-axis represents the relative content of immune cells. Different colors represent different types of immune cells, with a color legend provided on the right. B Heatmap showing the analysis of immune cell composition in normal tissue and tumor tissue of BNST patients. The x-axis represents the sample number, and the y-axis represents different types of immune cells. Different colors in the heatmap represent the relative content of immune cells. C Difference plot representing the difference in immune cell composition proportion between normal tissue (blue) and tumor tissue (red) of BNST patients. D Immune cell correlation graph. Each small square represents the correlation between two immune cells. Positive correlations are shown in red, and negative correlations are shown in blue. The darker the color, the higher the correlation. E-F Correlation analysis of immune cell components differentially correlated with NRG1 expression. The x-axis represents the NRG1 expression level, and the y-axis represents the content of immune cells. In this case, (E) represents resting neutrophils, and (F) represents M2 macrophages. G Lollipop plot of the correlation analysis between all immune cell components and NRG1 expression