Killing capacity analysis of tumor-infiltrating cytotoxic lymphocytes and impact on lymph node metastasis in differentiated papillary carcinoma of thyroid with the BRAF V600E mutation

Table 3 Relativity indexes of the differential killing capacity of NK cells and CTLs in tumor tissues and paracancerous tissues with varying levels of CCLNM in PTC

	Group B(n = 17)	Group C(n = 17)	Group D(n = 10)	F	P
CD3⁺P⁺(%)_T	8.21 ± 1.32	8.41 ± 1.78	11.05 ± 3.04	0.567	0.572
CD3⁺P⁺(%)_N	9.71 ± 1.6	14.64 ± 2.64	14.32 ± 5.62	0.954	0.394
t	-1.068	-2.249	-0.815
p	0.3	0.04*	0.436
CD3⁺G⁺(%)_T	19.66 ± 3.26	20.24 ± 3.37	23.76 ± 4.35	0.31	0.735
CD3⁺G⁺(%)_N	15.76 ± 2.75	20.7 ± 3.2	29.94 ± 9.36	2.097	0.136
t	1.842	-0.172	-0.807
p	0.083	0.866	0.441
CD8⁺P⁺(%)_T	7.87 ± 1.43	9.69 ± 1.91	8.85 ± 2.1	0.304	0.74
CD8⁺P⁺(%)_N	9.56 ± 1.62	9.82 ± 1.74	7.28 ± 2.53	0.439	0.648
t	-0.877	-0.059	0.519
p	0.393	0.954	0.616
CD8⁺G⁺(%)_T	25.71 ± 3.56	29.37 ± 3.62	31.54 ± 5.38	0.521	0.598
CD8⁺G⁺(%)_N	18 ± 2.16	22.16 ± 3.05	21.08 ± 3.48	0.675	0.515
t	1.963	2.869	1.88
p	0.066	0.012*	0.093
CD16-CD56⁺P⁺(%)_T	29.56 ± 4.38	25.96 ± 5.57	34.39 ± 5.34	0.565	0.573
CD16-CD56⁺P⁺(%)_N	37.49 ± 6.13	37.18 ± 6.65	27.59 ± 5.3	0.612	0.547
t	-1.761	-1.885	1.508
p	0.096	0.079	0.166
CD16-CD56⁺G⁺(%)_T	29.58 ± 4.23	29.96 ± 5.01	34.64 ± 6.07	0.257	0.775
CD16-CD56⁺G⁺(%)_N	36.16 ± 6.13	34.82 ± 6.52	27.45 ± 5.03	0.444	0.645
t	-1.895	-1.014	2.559
p	0.075	0.327	0.031*

Values are expressed as the mean ± standard error of the mean (SEM). Within-group comparisons
were made using paired t tests, and comparisons among groups were made using one-way
ANOVA, *represents significant differences (P < 0.05)

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