Table 4 Immunohistochemical findings, fluorescence in situ hybridization (FISH) and in situ hybridization (ISH) tests of 14 patients with hyalinizing clear cell carcinoma (HCCC)
Case no | Clear cell (%) | Nerve invasion | Necrosis | P40 | P63 | CK7 | CK5/6 | Ki-67 (%) | P16 (%) | EWSR1 (FISH) | EWSR1::ATF1 (FISH) | EBER (ISH) | HPV (ISH) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 50% | - | - | 4 +  | 4 +  | 2 +  | 4 +  | 3% | -(40%) |  +  |  +  | - | - |
2 | 10% | - | - | 4 +  | 4 +  | 1 +  | 4 +  | 2% | -(30%) |  +  |  +  | - | - |
3 | 5% |  +  |  +  | 2 +  | 3 +  | 4 +  | 4 +  | focal10% |  + (90%) |  +  |  +  | - | - |
4 | 10% | - |  +  | 1 +  | 1 +  | 4 +  | 2 +  | 2% | -(30%) |  +  |  +  | - | - |
5 | 90% | - | - | 1 +  | 1 +  | 4 +  | 4 +  | 1% | -(0) |  +  |  +  | - | - |
6 | 5% | - | - | 3 +  | 2 +  | 4 +  | 4 +  | 2% | -(10%) |  +  |  +  | - | - |
7 | 5% | - | - | 4 +  | 4 +  | 1 +  | 4 +  | 3% | -(20%) |  +  |  +  | - | - |
8 | 10% | - |  +  | 4 +  | 4 +  | 4 +  | 4 +  | 4% | -(30%) |  +  |  +  | - | - |
9 | 40% | - |  +  | 4 +  | 4 +  | 4 +  | 4 +  | 4% |  + (80%) |  +  |  +  | - | - |
10 | 10% | - | - | 2 +  | 3 +  | 0 | 3 +  | 1% | -(20%) |  +  |  +  | - | - |
11 | 10% | - |  +  | 2 +  | 1 +  | 1 +  | 1 +  | 10–20% | -(30%) |  +  |  +  | - | - |
12 | 20% | - | - | 3 +  | 4 +  | 4 +  | 4 +  | 3% | -(10%) |  +  |  +  | - | - |
13 | 20% | - | - | 4 +  | 4 +  | 4 +  | 4 +  | 4% | -(10%) |  +  |  +  | - | - |
14 | 50% | - | - | 2 +  | 4 +  | 3 +  | 4 +  | 3% | -(20%) |  +  |  +  | - | - |