Table 1 Clinical and pathological features of Mullerian adenosarcomas
From: Clinicopathological analysis of 22 Müllerian adenosarcomas and the sequencing of DICER1 mutation
case | Age(y) | Size(cm) | Site | Depth of myometrial invasion | Extreuterine disease | Stage | LVI | SO | Grade | HET | Treatment | Follow-up(mouth) | CD10 | ER | PR | Desmin | ki67 | Caldesmon | CyclinD1+ | DICER1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
case1 | 52 | 8.5 | Uterine | 100% | rectum | IVa | - | - | low | - | TH + BSO,CT | 20,NED | + | + | + | + | 10%-15% | + | - | - |
case2 | 47 | 13.6 | Uterine | - | left broad ligament, right fallopian tube mesanga, rectum, rectovaginal pouch, omentum | IVa | - | + | low | - | TH + BSO,CT | 20,NED | + | ... | ... | - | 40% | - | ... | - |
case3 | 36 | 7.5 | Uterine | < 50% | - | Ib | - | + | low | - | TH + BSO | 29,NED | + | + | + | + | 5%-10% | + | - | - |
case4 | 32 | 2.7 | Uterine | - | - | Ia | - | - | low | - | PE + TH + BSO,ET | 29,NED | + | ... | ... | + | 10% | + | ... | - |
case5 | 45 | 9.5 | - | - | Ia | - | - | low | - | TH + BSO | ... | + | + | + | + | 15% | - | + | - | |
case6 | 46 | 2 | Cervix | < 50% | - | Ib | - | - | low | - | PE + TH + BSO | 26,NED | + | + | + | + | < 5% | - | - | - |
case7 | 52 | 3.8 | Uterine | < 50% | mesostenium, transvers mesocolon | IIIb | - | - | low, undifferen-tiated | Rh | PE + TH + BSO,CT | 21,NED | + | + | + | + | 60% | ... | ... | - |
case8 | 47 | 4 | Cervix | < 50% | - | Ib | - | - | low | SCLE | PE + TH + BSO,CT | 4,NED | + | + | + | + | 5% | - | - | - |
case9 | 42 | 7 | Cervix | < 50% | pelvic lymphnodes | IIIC | + | - | high | - | TH + BSO,NCT + CT | ... | -/+ | -/+ | -/+ | -/- | -/<80% | - | -/+ | - |
case10 | 62 | 3.5 | Uterine | 100% | bilateralovary, omentum, mesostenium, rectum, bladder, sacral ligament | IVa | - | + | high | - | TH + BSO,NCT + CT | 14,NED | + | + | - | + | 5% | + | - | - |
case11 | 25 | 7.5 | Uterine | < 50% | - | Ib | + | + | undifferen-tiated | - | TH + BSO,CT | 12,NED | - | - | - | - | 40% | - | - | - |
case12 | 51 | ... | Uterine | - | - | Ia | - | - | low | - | PE + TH + BSO,CT | 30,NED | -/+ | ... | ... | ... | 5%/15% | ... | ... | - |
case13 | 42 | 10 | Left ovary | - | - | Ia | - | - | low | - | TH + USO | ... | + | + | + | + | 25% | - | + | - |
case14 | 44 | 6 | Uterine | > 50% | - | Ic | - | - | low | - | TH + BSO,CT | 14,NED | + | ... | ... | + | 20% | ... | ... | - |
case15 | 51 | 2 | Uterine | - | - | Ia | - | - | low | - | TH + BSO | ... | + | - | - | - | 20% | - | + | - |
case16 | 53 | 6 | Uterine | 100% | - | Ic | - | - | low | - | TH + BSO,CT | 36,NED | + | + | + | + | 30% | - | - | + |
case17 | 52 | 8.5 | Uterine | > 50% | lymphnodes | IIIc | + | + | undifferen -tiated | - | TH + BSO | ... | - | - | - | - | 40% | - | - | - |
case18 | 39 | 1.7 | Uterine | 100% | - | Ic | - | - | low | - | PE + TH + BSO,CT | 17,NED | - | - | + | - | 25% | - | - | - |
case19 | 54 | 1.5 | Uterine | < 50% | - | Ib | - | + | low | - | TH + BSO | ... | + | + | + | - | 70% | - | - | - |
case20 | 29 | 4 | Uterine | > 50% | - | Ic | - | - | low | - | PE + TH + BSO, CT | 15 NED | -/++ | ++/++ | +++/+ | ... | 5%-10% | -/- | -/- | - |
case21 | 26 | 12.5 | Uterine | > 50% | - | Ic | - | - | low | - | PE + TH + BSO, ET | 15 NED | -/++ | +++/+++ | +++/+++ | ... | 5%/15% | -/+ | -/- | - |
case22 | 42 | 1.8 | Uterine | > 50% | - | Ic | - | - | low | - | TH + BSO | 12 NED | - | - | - | ... | 10% | ... | + | - |